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Check rooms and rates
From149US$ /night
Check-in
28Dec2025Select date
Check-out
29Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

43 Columbia Street, Orlando, Florida, United States, 32806
-
Close to Lake Eola Park
Great
8.9
9.1
/10
4.6
4.3
/5

Rooms and Amenities

Hampton Inn & Suites Orlando/Downtown South - Medical Center offers 126 air-conditioned rooms with two queen or one king-sized Hampton beds. Each room includes a flat-screen TV, small refrigerator, microwave, coffee-making facilities, and free WiFi. Some rooms feature sofa beds and wet bars. Accessible rooms with visual alarms, lowered beds, and roll-in showers are available.

Dining Options

The hotel provides a free hot breakfast buffet daily. A snack bar and deli serve light meals and snacks throughout the day. Coffee and tea makers are available in all rooms.

Recreation Facilities

Guests have access to an outdoor pool and a fitness center. The business center offers computers, printing services, and complimentary newspapers. Conference space measuring 1128 square feet accommodates meetings for up to 35 people, equipped with an LCD projector, screen, and conference phone.

Location and Access

Located in downtown Orlando, the hotel is within walking distance of Arnold Palmer Hospital for Children and a 15-minute walk from Orange Avenue. Universal Orlando Resort and Universal Studios Florida are nearby attractions. Orlando Executive Airport is the closest airport. Self-parking costs $15 per day with in/out privileges.

Guest Services

Services include dry cleaning/laundry, contactless arrival via Hilton Honors app, and late check-out when available. The hotel accepts pets (2 maximum, 75 lbs max weight) for a fee of $75 for 1-4 nights or $125 for 5+ nights. Safety features include carbon monoxide detectors, fire extinguishers, smoke detectors, and first aid kits.

“I think this property stands out for its generous breakfast and practical perks like pet-friendliness and late check-out. The location near the medical center and downtown attractions also makes it a smart choice for many travelers. It's a balanced option for visitors to Orlando.”
Hotel logo
Grace WhitmanContent & Editorial Director at Familyhotels
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Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included
King Room Hearing Accessible
2 persons
36 m² 
1 King-size bed
Shower
Queen Room Two Queen Beds
2 persons
28 m² 
2 King Size Beds
Shower
King Room Non-Smoking
2 persons
33 m² 
1 King-size bed
Shower
King Room Sofa Bed Non-Smoking
2 persons
34 m² 
1 King-size bed and 1 Sofa bed
Shower
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Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Snack bar

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's buffet

Spa & Leisure

  • Outdoor swimming pool
  • Sun loungers
  • Leisure/ TV room

Room features

  • Air conditioning
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Media

  • Flat-screen TV
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Location

43 Columbia Street, Orlando, Florida, United States, 32806
Map view
43 Columbia Street, Orlando, Florida, United States, 32806
Nearby
Amusement Park
Delaney Street Playground
540 m
Hospital
Orlando Regional Medical Center
300 m
Orlando Regional-Lucerne
430 m
Hospital
Winnie Palmer Hospital for Women and Babies
570 m
Restaurants
Delaney's Tavern
450 m
1315 S Orange Ave
Lucy Bleuz Cafe
530 m
1321 Sligh Blvd
Incredibly Edible
530 m
1321 Sligh Blvd
Orlando Brewing
670 m
1301 Atlanta Avenue
Brick & Fire
780 m
1621 S Orange Ave Ste 108
Pizza Hut
780 m
1621 S Orange Ave
Subway
950 m
1742 S Orange Ave
7-Eleven
1.1 km
1823 S Orange Ave
Explore Orlando
Explore Local Highlights
Top Attractions
Activities
Dining
Entertainment
Orange County Regional History Center
20 minutes' walk
Historical exhibits detailing the region's past, featuring rotating displays and special programs for all ages.
Lake Eola Park
30 minutes' walk
A scenic park known for its swan boats, walking trails, and outdoor concerts, providing a relaxing escape from the city.
Amway Center
25 minutes' walk
Home to the Orlando Magic, this venue hosts major sporting events and concerts featuring world-renowned artists.
Outdoor Yoga at Lake Eola
30 minutes' walk
Relaxing outdoor yoga sessions at Lake Eola, ideal for rejuvenating amidst nature. Classes available weekly.
Biking along the Orlando Urban Trail
5 minutes' drive
A scenic biking trail offering an adventurous ride through the urban landscape with bike rentals easily accessible nearby.
Delaney's Tavern
6 minutes' walk
Casual eatery featuring classic American dishes and local craft beers in a warm and inviting atmosphere.
Lucy Bleuz Cafe
7 minutes' walk
Charming cafe known for its creative brunch offerings and artisan coffee, perfect for a cozy meal any time of day.
Dr. Phillips Center for the Performing Arts
20 minutes' walk
A stunning venue showcasing Broadway shows, concerts, and cultural performances. Check out the schedule for family-friendly events.
Mad Cow Theatre
20 minutes' walk
Local theater featuring a variety of performances, including drama and comedy. Ideal for a fun night out with friends.
Tips on navigating the city
City Centre
Orlando6 min  ·  500 m
Airports
Orlando Executive Airport (ORL)12 min  ·  7.4 km
Orlando International Airport (MCO)28 min  ·  18.1 km
Train
Church Street Station17 min  ·  1.4 km
Woodsmere Sub-Station15 min  ·  9.4 km
Get access to exclusive early booking discounts for your family’s upcoming getaway
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site (reservation might be needed) at USD 18 per day.
Internet
is available in for free.
Breakfast
All visitors are offered a buffet breakfast for a fee. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Languages
Spanish
Number of floors:
6
Number of rooms:
126
FAQs
About Hampton Inn & Suites Orlando/Downtown South - Medical Center
What popular attractions are near Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Nearby attractions include Orange Avenue (1 km), Amway Center (1 km), and Universal Orlando Resort (8 km).
What are the check-in and check-out times at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Check-in is from 15:00 and check-out is by 11:00.
Is parking available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Private parking is available on-site for $18.00 per day, and reservation is needed.
What room amenities are provided at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Rooms include air conditioning, a flat-screen TV, a small refrigerator, and coffee-making facilities.
What breakfast options are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The hotel offers a complimentary hot breakfast daily and Hampton's On the Run Breakfast Bags available Monday through Friday.
Does Hampton Inn & Suites Orlando/Downtown South - Medical Center have a fitness center?
Yes, the hotel features an on-site fitness center for guest use.
Are pets allowed at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Yes, the hotel allows pets with additional charges applicable.
Does Hampton Inn & Suites Orlando/Downtown South - Medical Center provide business services?
The hotel offers a business center and meeting facilities equipped with audio-visual equipment.
How far is Hampton Inn & Suites Orlando/Downtown South - Medical Center from Orlando Executive Airport?
The hotel is located 5 km from Orlando Executive Airport.
What are the key highlights of Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Highlights include free Wi-Fi, an outdoor pool, luggage storage, and a 24-hour reception.
Are there any dining options on-site at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The hotel features a snack bar/deli for guests.
Is Hampton Inn & Suites Orlando/Downtown South - Medical Center accessible for guests with limited mobility?
The hotel provides wheelchair access within its premises.

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